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This assumption can be partially supported by the evidence that the expression of rate-limiting enzyme for synthesizing NAD + , NAMPT, is not altered in KIRC patients while expression of NAPRT (Nicotinate phosphoribosyltransferase) and QPRT (Quinolinate phosphoribosyltransferase) is downregulated

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Inhibition of miR-29b-3p or miR-378g upregulates NNMT expression and promotes osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs), whereas overexpression of miR-29b-3p or miR-378g downregulates NNMT expression and inhibits osteogenic differentiation of BMSCs