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AM833 is a novel agonist of calcitonin family G protein-coupled receptors: Pharmacological comparison with six selective and nonselective agonists

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Color:240 Light Medium

Interestingly, introduction of carboxylic acid groups to RT slows down its reaction kinetics towards GSH comparing to RT-NH 2 and TQG-CN (Table 2), presumably due to the charge repulsion between the carboxylic acid groups and the anionic GSH