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and step 3: stirring to dissolve and clarify the prepared solution, adding water for injection to full amount, and adjusting the pH value to 6.0-7.0 by using a 10% sodium hydroxide solution

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Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation