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In summary, we could envisage prompt activation of the vascular collaterals (particular mRNA expression genes, same in duodenum and colon) as a particular target resolved by the BPC 157 therapy in fistulas healing compatible also with resolution of the multiorgan failure of even deadly occlusion/occlusion-like syndromes by BPC 157 therapy (51-66)

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Furthermore, a study using 3D cultures of primary human ADPKD cells demonstrated inhibition of Notch3 via gamma secretase resulted in reduced cyst proliferation in vitro [127]