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In another study, continuous infusion of hANP, a potent endogenous natriuretic and diuretic agent at a dose of 50 ng/kg/min in patients with acute ischemic renal failure following complex cardiac surgery, resulted in improved renal function, reduced need for dialysis, and prolonged dialysis-free survival [ 117 ]

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If a sachet is accidentally torn or gel is spilled during application, that dose is lost