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Using a training model to decode complex features (texture, shape, etc.) in CT images, key metabolic phenotypes, such as PLIN2 expression and ferroptosis sensitivity, can be predicted, and patients with “high-risk” metabolic characteristics (such as DCCD tendency) can be identified before treatment (Deng et al., 2025)

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doi: 10.1111/j.1474-9726.2005.00168.x