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507 The prototypical Rrf2-family repressor is proteobacterial IscR, an Fe–S cluster regulator that contains a 2Fe–2S cluster ligated by three Cys and one His and controls the biogenesis of Fe–S clusters in cells
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It supports the absorption of calcium, magnesium, and phosphate, contributes to brain and nervous system health, strengthens immune function, improves mood, and may help reduce the risk of seasonal depression
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