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Full article: Integrated approach to reducing polypharmacy in older people: exploring the role of oxidative stress and antioxidant potential therapy

Nanozyme Design for Ferroptosis–Cuproptosis Regulation Nanozymes are nanomaterials endowed with enzyme-mimetic catalytic activity that are capable of catalyzing substrate conversion under physiologically relevant conditions and eliciting defined biological effects

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Copper is an essential cofactor for numerous key enzymes involved in tissue remodeling, including lysyl oxidase (which cross-links collagen and elastin fibers), superoxide dismutase (the primary intracellular antioxidant enzyme), and cytochrome c oxidase (the terminal enzyme of mitochondrial respiration)