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Furthermore, p53 regulates the transcription of microRNAs, particularly members of the miR-34 family
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BPH leads to lower urinary tract symptoms (LUTS), which include voiding symptoms (hesitancy, intermittency, poor stream, straining and terminal dribble) and storage problems (nocturia, urgency, and increased frequency) that negatively impact the quality of life (QOL) of patients, family members, and disrupts work performance [1,2,3,4]