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These M1 cells are characterized by MHC class II, CD86 and CD40 upregulation [14,15], downregulation of mannose receptor (CD206), their ability to engulf and digest microbes, secrete Pro-inflammatory/T helper 1 (Th1)-promoting cytokines such as IL-12, IL-1β, IL- 6, TNF-α production of microbicidal molecules
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Tamaño:500 gramos (1,1 libras)
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