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283 Notably, 1026 sites of lactylated proteins were identified in myocardial tissues from I/R rats by lactylation modification omics and were prominently enriched in the TCA cycle pathway

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While there’s no direct evidence that IGF-1 causes cancer, it can theoretically accelerate the growth of existing or dormant tumors , especially in hormone-sensitive tissues like the breast, prostate, or colon

The acetylated form protects the reduced glutathione molecule from gastric degradation and inactivation