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Conclusion Although the current evidence on DEHP-induced BRCA is limited mainly to epidemiological studies and cell/animal experiments, it is undeniable that DEHP, as a plasticizer widely accessible in daily life, has a non-negligible impact on human health

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The structures of several remodeler complexes 38,39,40,41 provide a foundation for understanding how these enzymes are regulated, how their different subunits and domains integrate external input and how they finetune the coupling of DNA translocation to desired outcomes in the chromatin landscape