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FOXO4-DRI's ability to selectively eliminate these cells provides researchers with tools for studying how senescent cell burden contributes to aging phenotypes and age-related diseases
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It should be noted that recent studies reported that some new GRK4 variants are associated with hypertension ( GRK4 rs1644731 ), both hypertension and diabetes ( GRK4 rs1557213 ), or cardiovascular disease risk and diabetes ( GRK4 rs60314379 ) [104, 105, 115]
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