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Also, it has been shown that the hepatocyte nuclear factor-3 (HNF-3), HNF-4, and CCAAT/enhancer-binding protein (C/EBP), nuclear factor I (NFIA1.1, NFIB2, NFIC1, NFIC2, and NFIX) play important roles in regulating the expression CYP3A4 (Rodriguez-Antona et al., 2003

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Once it enters your bloodstream, your body breaks it down at a steady rate, influenced by factors such as body size, liver function, and overall health