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The Role of Pfmdr1 and Pfcrt in Changing Chloroquine, Amodiaquine, Mefloquine and Lumefantrine Susceptibility in Western-Kenya P. falciparum Samples during 2008–2011 | PLOS One

This creates two downstream problems: (1) SAM depletion reduces the availability of methyl groups for other critical methylation reactions, including DNA and histone methylation

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