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Such remissions are understood to be mediated via the immune system [38], by triggers that remain somewhat mysterious, though there are clues: some of the cases of spontaneous remission have followed on either from vaccination [15, 16, 39], or after viral infections [14, 17, 26, 30], and sometimes even with occurrence of other haematological neoplasms [13, 18, 27, 32], thrombocytopenia [35] or bone marrow necrosis [19]
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