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Cuando existen presiones adicionales como estrés emocional o físico, radiación, infecciones, una dieta poco saludable, toxinas, metales pesados ​​y la invasión de patógenos, los niveles celulares de glutatión pueden agotarse rápidamente, lo que puede provocar daño celular

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HSPA2 is a testis-enriched HSP70 member that is mainly distributed in spermatocytes and spermatids, where it participates in spermatogenesis and contributes to the quality control of spermatid proteins