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Subsequently, repair or degeneration occur, which depend on multiple factors such as the type and extent of damage, the immune system, the genetic susceptibility to disc degeneration, which is linked with age, the biomechanical (functional) condition that is created by the injury, and finally the type of treatment: conservative (disc loading) or operative (disc unloading)
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Anti-AChR antibodies are typically generated through T-cell- and B-cell-mediated pathogenic mechanisms, which activate the complement system (4,5)
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