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5.4 Toxic diffuse goiter (Graves’ disease) In Graves’ Disease (GD) and its ocular manifestation, Graves’ Orbitopathy (GO), ferroptosis affects cell metabolism and iron balance

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The introduction of a second hydroxyl group into the 2 or 4 position of a phenol provides a higher reactivity than that observed for monohydroxy phenols due to the resonance-stabilized aryloxyl radical ArO • (Figure 5) [10,31]