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Importantly, some ferroptosis inducers can also act synergistically with most traditional drugs (e.g., lapatinib) to suppress the tumor growth (Table S1) [263]

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Many of the enzymes like monooxygenases are found in the endoplasmic reticulum membrane, but others such as the dehydrogenases for example alcohol dehydrogenases and peroxidases located in the cytoplasm, while still others such as monoamine oxidase are localized in mitochondria