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Target 2 : AngIII conversion to AngIV (and AngIV analogs) acting at IRAP results in IRAP inhibition thus resulting in the potentiation of several memory enhancing peptides including AngIV, vasopressin, oxytocin, somatostatin and cholecystokinin-8

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Introduction Traumatic brain injuries (TBIs) constitute a significant public health issue and a major source of disability and death in the United States and worldwide [1]