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2.1 Antioxidant function of GSH The antioxidant function of GSH is accomplished largely by GSH peroxidase (GPx)-catalyzed reactions, which reduce hydrogen peroxide and lipid peroxide as GSH is oxidized to GSSG

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Next, in order to explore the predictive potential of GPX7 expression as a chemotherapy response predictor , we performed ROC (Receiver Operating Characteristic) in an independent GBM dataset (n = 454) 45 treated with multiple chemotherapeutic agents (Supplementary Fig