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The authors conclude “[o]ur findings indicate that opioid treatment for pain can have adverse effects on labor productivity and employment, even precipitating more permanent separation from the labor force through SSDI claiming.…[W]here medically possible, decreased reliance on opioid analgesics for pain treatment (and possibly increased use of effective non-opioid pain therapies with fewer adverse effects) can not only improve patients’ health, but also work-related functioning and labor outcomes.” The research reported herein was performed pursuant to grants DRC12000002-05 and RDR18000003 from the US Social Security Administration (SSA), funded as part of the Retirement and Disability Research Consortium, from grant P01AG005842 from the National Institute on Aging, and a gift from Owen and Linda Robinson