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“Regarding the CAT levels, a reduction was noted in the MTX group compared to the Control group, whereas an insignificant increase was observed in the Vit B12 and MTX+Vit B12 groups upon comparison with the Control group

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We then stimulated the transfected cells with human TSH and found that the cAMP level induced by the truncated TSHR is significantly lower than that induced by WT TSHR (Fig