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[1] A common starting regimen in adults with normal renal and hepatic function is 1 mL intramuscularly once or twice weekly, titrated every four weeks according to biochemical markers such as fasting lipid panel, liver transaminases, and serum carnitine

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Additionally, KYN could also activate the aryl hydrocarbon receptor (AhR) signaling, resulting in neuroinflammation and depressive behavior in mice 15