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Swirl gently until the cake fully dissolves into a clear, colourless solution

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In the folate/vitamin B12‐dependent mechanism, folate in the form of 5‐methyl tetrahydrofolate, derived from 5,10‐methylene tetrahydrofolate reductase catalyzed tetrahydrofolate modification, donates a methyl group to Hcy catalyzed by the vitamin B12‐dependent enzyme methionine synthase to form methionine