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Cleavage by the rhomboid protease presenilin-associated rhomboid-like protein (PARL) and/or matrix-AAA (m-AAA) proteases results in 52/48 kDa cleaved variants of PINK1
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Sample acquisition was conducted in full-scan mode, with the spray voltage set to 3 kV (negative) or 3.5 kV (positive), the capillary temperature to 320°C, and the HESI probe to 300°C, sheath gas to 40U, the AUX gas to 8U, and the sweep gas to 1 unit, and resolving power to 120,000
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