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Genetic and Mechanistic Insights Inform Amyotrophic Lateral Sclerosis Treatment and Symptomatic Management: Current and Emerging Therapeutics and Clinical Trial Design Considerations | CNS Drugs | Springer Nature Link

This might also lead to pain in the abdominal and pelvic area, breath shortness, nausea, vomiting, diarrhea, infrequent urination, with high swelling in the limbs

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Zou et al