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2017 Cell study used 5 mg/kg intraperitoneal injection three times per week in aged mice, with treatment periods of several weeks — the three-times-weekly dosing suggests the peptide maintains sufficient functional concentrations for at least 48-72 hours per dose (PMID: 28340339)

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Dihexa is studied in laboratory research for its interaction with HGF/c-Met receptor pathways linked to neurotrophic and synaptic-connectivity signaling