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(Wang et al., 2021) identified miR-29b-3p and miR-378g as potential miRNAs upstream of NNMT by bioinformatics analysis

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Key Preclinical Study (Neelakantan et al., 2018): Treatment in diet-induced obese mice produced progressive body weight loss, reduced white adipose tissue mass and adipocyte size, decreased total cholesterol, and no changes in food intake — effects were metabolic, not appetite-driven