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Commonly reported side effects include: Nausea, vomiting, and diarrhoea — typical of GLP-1 receptor agonism Reduced appetite and early satiety Increased heart rate, as observed with GLP-1 receptor agonists as a class Risk of hypoglycaemia, primarily when used alongside insulin or sulfonylureas rather than as monotherapy Delayed gastric emptying, which may affect the absorption of orally administered medicines taken concurrently Risk of gallbladder disease, including cholelithiasis, a recognised class effect of GLP-1 receptor agonists [9] [10] Gastrointestinal discomfort, which may be dose-dependent BPC-157, while generally described as well-tolerated in animal studies, lacks robust human safety data
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