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Example 2 7-Cyclopentyl-N, N-dimethyl-2-((5-(piperazin- 1 -yl)pyridin-2-yl-3,4,6-d 3 )amino)-7H- pyrrolo[2,3-dJpyrimidine-6-carboxamide Step 1: tert-Butyl 4-(6-nitropyridin-3-yl-2,4,5-d3)pipera/.ine-l -carboxylate To a stirred solution of 5-bromo-2-nitropyridine-3,4,6-d3 (commercially available) (3.0 g, 14.6 mmol) and teri-bulyl pipera/ine- 1 -carboxylate (4.08 g, 21.9 mmol) in DMSO (35 ml) were added TEA (2.22 g, 21.9 mmol) and lithium chloride (0.63 g, 14.9 mmol)
Anti-Wrinkle Eye Cream
Selection:240 Vegetarian Capsules
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