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The importance of plasma tHcy as a marker for a subgroup was shown in a randomized trial (VITACOG) on elderly people with mild cognitive impairment: In VITACOG, a combination of B vitamins (800 μg folic acid, 500 μg B12, and 20 mg vitamin B-6/d) slowed brain atrophy and cognitive decline over a 2-y period (59, 60), but only those whose baseline plasma tHcy was above the median (∼11 µmol/L) benefitted from the B vitamins

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It modulates inflammatory responses in the gut

Palmitoyl Tripeptide