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[DOI] [PubMed] [Google Scholar] 72.Staropoli N., Ciliberto D., Botta C., Fiorillo L., Grimaldi A., Lama S., Caraglia M., Salvino A., Tassone P., Tagliaferri P

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The more recent REDUCE-IT trial (n = 8,179) found that 4 g/day of icosapent ethyl (a purified eicosapentaenoic acid ethyl ester) significantly reduced cardiovascular death (HR 0.75, 95% CI 0.68–0.83), myocardial infarction, and stroke in high-risk individuals with elevated triglycerides despite statin therapy