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In a longitudinal cohort human study on 719 patients taking long-term warfarin, high homocysteine levels (≥17.2 μmol/L) and serum folate (≥11.9 nmol/L) were not associated with bleeding events, but both were associated with cardiovascular events (myocardial infarction, ischemic stroke, peripheral arterial emboli) [288] (Table 2)
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Lancet 303 , 1234–1235 (1974)
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