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Dosing regimens have ranged from 350 µg per week (in vegetarians) to 2000 µg per day in a study including patients with pernicious anaemia, with the most common daily dose being 1000 µg per day

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Cyanocobalamin works fine in many clinical contexts (and is the standard for injections), but as a daily supplement for long-term optimization, methylcobalamin is more direct and more commonly preferred by performance-oriented clinicians