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Senescent-like microglia, in contrast, limit remyelination through SASP that involves the release of multiple inflammatory mediators, including CCL11, CXCL9, and CCL5, and increased expression of IL-2, leading to impaired remyelination in mouse models ( Here, we review the heterogeneity of glial cells and glioinflammatory responses in different contexts linked to cellular senescence
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Typically, it is supplied in glass vials that contain 1 ml of a sterile, clear, and colorless solution for injection
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