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The experimental and surgical procedures for the large animal studies were approved by the Animal Ethics Committee of the Shanghai Jiaotong University School of Medicine and were carried out in compliance with the regulations and guidelines of the Shanghai Jiao Tong University Institutional Animal Care and with the AAALAC and IACUC guidelines

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Disruption of this process leads to the accumulation of dysfunctional mitochondria, increased oxidative stress, activation of inflammatory pathways, and progressive cellular dysfunction, thereby contributing to the pathophysiology of disorders such as endometriosis