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Therefore, at least three days before the treatment it is advisable to stop taking these substances

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[89Zr]Zr-DFO-avelumab tumor-accumulation not so much correlated to PD-L1 expression in the tumor, but did strongly indicated an immune suppressive microenvironment with increased regulatory T-cell density and reduced CD303+ plasmacytoid dendritic cell density, and (consequently?) with pathological responses