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This initial review and subsequent contributions to the literature suggest that gut microbial β-glucuronidase enzymes are especially important in total estrogen circulation (5–8)

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(2) limited clinical data exist, with most studies featuring short-term evaluations (weeks-months) that preclude comprehensive safety and efficacy assessment ( 9.3 Bioactive factors used in IVD repair strategies The aim of injecting seed cells into the IVD is to promote the synthesis of proteoglycan and the recovery of disc height