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Some documented traditional uses of Goldenseal include: REF#2521 REF#2522 Eye health Digestive function Gut health Heart function Immune function Lung function Skin health The main active plant compounds in Goldenseal root are isoquinoline alkaloids such as: Hydrastine (1.5–4%) Berberine (2.5%) Canadine (0.5%) And other alkaloids These plant compounds have been shown to be responsible for much of Goldenseal’s potential health benefits