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In the porcine jejunum epithelial cell line (IPEC-J2), CT decreased the inflammatory response mediated by peptidoglycan, improved ZO-1 and claudin levels, and increased epithelial resistance, ensuring intestinal integrity and functionality ( Despite the important findings on the role of CT as a compound with an anti-obesity activity in mice, further studies are still needed to determine its effects on other systems that regulate body weight, such as muscle tissue and the central nervous system ( In summary, the results presented in this study demonstrate the anti-hyperglycemic, anti-lipidemic, and anti-inflammatory effects of CT against HFD-related obesity in mice

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[DOI] [PMC free article] [PubMed] [Google Scholar] 52.Mahmood I