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Dosage: Nasal Spray Vs Injections Over-The-Counter Methyl B12 Nasal Sprays Synchronicity Health’s Methyl B-12 Nasal Spray is designed for daily wellness support: Recommended serving : Two sprays per day, totaling 408 mcg of methylcobalamin Can be taken as: One spray in each nostril once daily, or Two sprays in one nostril, depending on preference and guidance from your practitioner For most performance-focused users, consistent daily dosing works better than sporadic megadoses